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KMID : 0357119940160020149
Korean Journal of Immunology
1994 Volume.16 No. 2 p.149 ~ p.156
Phagocytic Activity of cultured Type-1 and Type-2 Astrocytes of Neonatal Rat Brain
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Abstract
It is well known that astrocytes are involved in the neural communication, the survival of neuron, neurite outgrowth, and the process of regeneration. In order to elucidate the phagocytosis on cultured type-1 and type-2 astrocytes of neonatal rat
brain,
flow cytometric studies were performed after two types of astrocytes were treated with latex beads for 2 hours. The phagocytic activities of type-1 and type-2 astrocytes were 72.5% and 51.4%, respectively which were higher than those of
peritoneal
macrophages942.4%). The above results indicate that both the cultured type-1 and type-2 astrocytes have remarkable phagocytosis of foreign material and type-1 astrocytes have more phagocytic activity than type-2 astreocytes.
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